Self-examination of the testes is important for early detection of testicular cancer. The most common method of early detection is performing a monthly exam. Since TC is usually isolated to a single testicle, comparison of your testicle with the other can be helpful. It is normal for one testicle to be slightly larger than the other. Your focus should be noticing any changes from the previous month.
The best time to self-exam is after a warm bath or shower when the scrotal skin is relaxed.